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020 _a9781493918720
_9978-1-4939-1872-0
024 7 _a10.1007/978-1-4939-1872-0
_2doi
049 _aAlfaisal Main Library
050 4 _aQD431-431.7
072 7 _aPSBC
_2bicssc
072 7 _aSCI007000
_2bisacsh
082 0 4 _a572.6
_223
245 1 0 _aClinical Proteomics
_h[electronic resource] :
_bMethods and Protocols /
_cedited by Antonia Vlahou, Manousos Makridakis.
250 _a2nd ed. 2015.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Humana Press,
_c2015.
300 _aXIII, 278 p. 40 illus., 28 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology, Methods and Protocols,
_x1064-3745 ;
_v1243
505 0 _aBiological Sample Collection For Clinical Proteomics - Existing SOPs -- Targeting The Proteome Of Cellular Fractions: Focus on Secretome -- Preparation Of Urinary Exosomes: Methodological Issues For Clinical Proteomics -- Sample Treatment Methods Involving Combinatorial Peptide Ligand Libraries For Improved Proteomes Analyses -- Glycoprotein Enrichment Method Using A Selective Magnetic Nano-Probe Platform (MNP) Functionalized With Lectins -- The Latest Advancements In Proteomic Two-Dimensional Gel Electrophoresis Analysis Applied To Biological Samples -- 2DE Maps In The Discovery Of Human Autoimmune Kidney Diseases: The Case of Membranous Glomerulonephritis -- MALDI-Imaging Mass Spectrometry on Tissues -- Laser Capture Microdissection Of Fluorescently Labeled Amyloid Plaques From Alzheimer’s Disease Brain Tissue For Mass Spectrometric Analysis -- Urine Sample Preparation And Fractionation For Global Proteome Profiling By LC-MS -- Methods In Capillary Electrophoresis Coupled To Mass Spectrometry For The Identification Of Clinical Proteomic/Peptidomic Biomarkers In Biofluids -- Quantification Of Proteins In Urine Samples Using Targeted Mass Spectrometry Methods -- Statistical Issues In The Design And Planning Of Proteomic Profiling Experiments -- Integrating Proteomics Profiling Data Sets – A Network Perspective -- The European Medicines Agency Experience With Biomarker Qualification.
520 _aThis second edition expands upon the previous edition with current, detailed developments in the field and brings together a multi-disciplinary team of leading researchers to provide their latest protocols for clinical proteomics analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.   Authoritative and Practical, Clinical Proteomics: Methods and Protocols, Second Edition presents  approaches that will serve as a reliable guide to researchers, including clinicians, chemists, molecular biologists, bioinformaticians and computational, biologists, and investigators working on biomarker development.
650 0 _aLife sciences.
650 0 _aProteomics.
650 0 _aProteins.
650 1 4 _aLife Sciences.
650 2 4 _aProtein Science.
650 2 4 _aProteomics.
655 7 _aElectronic books.
_2local
700 1 _aVlahou, Antonia.
_eeditor.
700 1 _aMakridakis, Manousos.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781493918713
830 0 _aMethods in Molecular Biology, Methods and Protocols,
_x1064-3745 ;
_v1243
856 4 0 _uhttp://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-1-4939-1872-0
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