000 04324nam a22005535i 4500
001 978-3-319-01225-4
003 DE-He213
005 20160615101638.0
007 cr nn 008mamaa
008 150205s2015 gw | s |||| 0|eng d
020 _a9783319012254
_9978-3-319-01225-4
024 7 _a10.1007/978-3-319-01225-4
_2doi
049 _aAlfaisal Main Library
050 4 _aRC346-429.2
072 7 _aMJN
_2bicssc
072 7 _aMED056000
_2bisacsh
082 0 4 _a616.8
_223
245 1 0 _aCerebrospinal Fluid in Clinical Neurology
_h[electronic resource] /
_cedited by Florian Deisenhammer, Finn Sellebjerg, Charlotte E Teunissen, Hayrettin Tumani.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2015.
300 _aXIV, 441 p. 75 illus., 51 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1. Introduction -- 2. History of CSF -- 3. Anatomy of CSF-related spaces -- 4. Physiology of CSF -- 4.1. CSF production -- 4.2. CSR resorption -- 4.3. Biological function of CSF -- 5. CSF collection -- 5.1. Techniques -- 5.2. Counter-indications and complications -- 5.3. Preanalytical aspects -- 6. Methods -- 6.1. Cell counts and cell staining -- 6.2. Glucose and Lactate -- 6.3. Proteins -- 6.4. Albumin -- 6.5. Immunoglobulins -- 6.6. Detection of infectious agents -- 6.7. Immunohistochemistry -- 6.8. Others (biomarkers) -- 7. CSF in clinical syndromes -- 7.1. Inflammatory disease of the CNS -- 7.1.1. Acute (bacterial, viral meningitis) -- 7.1.2. Chronic (MS) -- 7.2. Inflammatory diseases of the PNS -- 7.2.1. Acute (GBS, Neuroborreliosis) -- 7.2.2 Chronic (CIDP) -- 7.3. Neoplastic and paraneoplastic neurological disorders -- 7.4. Dementias and degenerative disorders -- 7.5. Cerebral bleedings -- 7.6. CSF rhinorrhoea and otorrhoea. 8. Guidelines.
520 _aThe cerebrospinal fluid (CSF) is an invaluable diagnostic tool in clinical neurology, not only in the evaluation of inflammatory, degenerative, and malignant diseases of the nervous system, but also in the diagnosis of all forms of cerebral and subarachnoidal bleedings. The CSF can be easily obtained by lumbar puncture and a set of basic analyses can be conducted using relatively simple laboratory methods. By combining different CSF parameters, a wide range of diagnostic entities can be identified. However, properly interpreting the test results requires a high level of expertise and cannot be achieved by just reporting on individual analytic values. This book covers essential aspects of cerebrospinal fluid analysis and its use in the diagnosis of common neurological diseases. The first part addresses preclinical aspects such as the history of CSF, as well as the anatomical, physiological, and biological background of this valuable fluid. In addition, CSF collection, its preanalytical and methodological implications, and the increasing number of disease-specific markers in CSF are discussed in detail. Lastly, CSF analyses are put into context with clinical syndromes, demonstrating their diagnostic value in neurological clinical practice. Cerebrospinal Fluid in Clinical Neurology helps readers understand the preanalytical and analytical aspects of CSF diagnostics and offers a valuable reference guide for interpreting CSF results during the clinical work-up for neurological patients.  .
650 0 _aMedicine.
650 0 _aLaboratory medicine.
650 0 _aNeurology.
650 0 _aNeurosurgery.
650 0 _aPathology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aNeurology.
650 2 4 _aPathology.
650 2 4 _aLaboratory Medicine.
650 2 4 _aNeurosurgery.
655 7 _aElectronic books.
_2local
700 1 _aDeisenhammer, Florian.
_eeditor.
700 1 _aSellebjerg, Finn.
_eeditor.
700 1 _aTeunissen, Charlotte E.
_eeditor.
700 1 _aTumani, Hayrettin.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319012247
856 4 0 _uhttp://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-3-319-01225-4
912 _aZDB-2-SME
942 _2lcc
_cEBOOKS
999 _c262445
_d262445