000 03201nam a22005295i 4500
001 978-3-319-05161-1
003 DE-He213
005 20160615105757.0
007 cr nn 008mamaa
008 140624s2014 gw | s |||| 0|eng d
020 _a9783319051611
_9978-3-319-05161-1
024 7 _a10.1007/978-3-319-05161-1
_2doi
049 _aAlfaisal Main Library
050 4 _aRM1-950
072 7 _aMMG
_2bicssc
072 7 _aMED071000
_2bisacsh
082 0 4 _a615
_223
245 1 0 _aMammalian Transient Receptor Potential (TRP) Cation Channels
_h[electronic resource] :
_bVolume II /
_cedited by Bernd Nilius, Veit Flockerzi.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2014.
300 _aXI, 565 p. 69 illus., 50 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aHandbook of Experimental Pharmacology,
_x0171-2004 ;
_v223
505 0 _aTRPs as Special Cell Sensors: Temperature Sensing with TRPs -- TRPs in Mechano-sensing and Volume Regulation -- TRPs as Chemosensors (ROS, RNS, RCS, Gasotransmitters) -- Photosensitive TRPs -- TRPs in Taste and Chemesthesis -- Pain -- TRPs in Hearing -- TRPs in Olfaction -- TRP Structure -- Pain.- TRPs in Hearing -- TRP in Olfaction -- General Topics: Evolutionary Conserved, Multitasking TRP Channels-lessons From Worms and Flies.- TRPs as Novel Drug Targets -- TRPs in Endocrinology -- TRPs Modulation by Toxins -- TRPs and Phosphoinositides -- TRPs Modulation by Natural Compounds -- What do we Really Know and What do we Need to Know: Controversies, Perspectives, Surprises.
520 _aIn this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
650 0 _aMedicine.
650 0 _aHuman physiology.
650 0 _aMolecular biology.
650 0 _aPharmacology.
650 1 4 _aBiomedicine.
650 2 4 _aPharmacology/Toxicology.
650 2 4 _aHuman Physiology.
650 2 4 _aMolecular Medicine.
655 7 _aElectronic books.
_2local
700 1 _aNilius, Bernd.
_eeditor.
700 1 _aFlockerzi, Veit.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319051604
830 0 _aHandbook of Experimental Pharmacology,
_x0171-2004 ;
_v223
856 4 0 _uhttp://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-3-319-05161-1
912 _aZDB-2-SBL
942 _2lcc
_cEBOOKS
999 _c271076
_d271076