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001 978-1-61737-973-4
003 DE-He213
005 20160615111401.0
007 cr nn 008mamaa
008 101216s2011 xxu| s |||| 0|eng d
020 _a9781617379734
_9978-1-61737-973-4
024 7 _a10.1007/978-1-61737-973-4
_2doi
049 _aAlfaisal Main Library
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.6
_223
245 1 0 _aMale Germline Stem Cells: Developmental and Regenerative Potential
_h[electronic resource] /
_cedited by Kyle E. Orwig, Brian P. Hermann.
264 1 _aTotowa, NJ :
_bHumana Press :
_bImprint: Humana Press,
_c2011.
300 _aXVIII, 262 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aStem Cell Biology and Regenerative Medicine
505 0 _aForeword -- Part I – Germline developmental potential -- 1. Primordial germ cells to EG cells, Peter Donovan -- 2. Pluripotent stem cells from SSCs, Marco Seandel, Ilaria Falciatori, and Shahin Rafii -- 3. ES cells to gametes, Sonya M. Schuh-Huerta and Renee A. Reijo Pera -- Part II – Spermatogonial stem cells -- 4. Morphometric description of the SSC pool in mammals, Dirk G. de Rooij -- 5. Spermatogonial stem cell transplantation and culture, Jonathan A. Schmidt and Ralph L. Brinster -- 6. Spermatogonial stem cell culture and in vitro assay, Makoto C. Nagano and Jonathan R. Yeh -- 7. Molecular signaling in SSCs, Olga M. Ocón-Grove and Jon M. Oatley -- 8. Spermatogonial stem cell niche, Shosei Yoshida -- Part III – Translation and regenerative potential of spermatogonial stem cells in higher primates -- 9. Gonadotoxic therapies: effects on spermatogenesis and fertility, Gunapala Shetty, Gensheng Wang, and Marvin L. Meistrich -- 10. Testicular xenografting, Stefan Schlatt, Jose R Rodriguez-Sosa and Ina Dobrinski -- 11. SSC transplantation in primates, Brian P. Hermann and Kyle E. Orwig.
520 _aScientists investigating germ cells have, over the past 15 years, originated discoveries and innovations that give us valuable insights into the mechanisms that regulate not just stem cell function, but human development in its widest sense. With contributions from some of the leading researchers in the field, Male Germline Stem Cells: Developmental and Regenerative Potential assesses the implications of these discoveries for understanding the fundamental biology of germline stem cells as well as their potential for human stem cell-based therapies. This monograph covers many of the fundamental issues now being explored by today’s generation of stem cell researchers, including the field’s potential for regenerative medicine. Ranging from an assessment of the pluripotency of primordial germ cells and their possible applications in treating testicular cancer, to the recovery of once-mordant fertilization-competent sperm, this volume has it all. It is a reference point for any scientist involved in related research as well as being a timely summation of what could prove to be a hugely exciting and very fruitful area of inquiry.
650 0 _aLife sciences.
650 0 _aCancer research.
650 0 _aBiotechnology.
650 0 _aReproductive medicine.
650 0 _aCell biology.
650 0 _aBiomedical engineering.
650 1 4 _aLife Sciences.
650 2 4 _aCell Biology.
650 2 4 _aBiotechnology.
650 2 4 _aBiomedical Engineering.
650 2 4 _aCancer Research.
650 2 4 _aReproductive Medicine.
655 7 _aElectronic books.
_2local
700 1 _aOrwig, Kyle E.
_eeditor.
700 1 _aHermann, Brian P.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781617379727
830 0 _aStem Cell Biology and Regenerative Medicine
856 4 0 _uhttp://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-1-61737-973-4
912 _aZDB-2-SBL
942 _2lcc
_cEBOOKS
999 _c287661
_d287661