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001 978-0-387-84856-3
003 DE-He213
005 20160615111921.0
007 cr nn 008mamaa
008 100301s2009 xxu| s |||| 0|eng d
020 _a9780387848563
_9978-0-387-84856-3
024 7 _a10.1007/978-0-387-84856-3
_2doi
049 _aAlfaisal Main Library
050 4 _aR-RZ
072 7 _aMBGR
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
245 1 0 _aHigh Resolution EPR
_h[electronic resource] :
_bApplications to Metalloenzymes and Metals in Medicine /
_cedited by Lawrence Berliner, Graeme Hanson.
264 1 _aNew York, NY :
_bSpringer New York,
_c2009.
300 _aXXV, 666 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aBiological Magnetic Resonance,
_x0192-6020 ;
_v28
505 0 _aHIGH-RESOLUTION EPR METHODS -- Advanced Pulse EPR Methods for the Characterization of Metalloproteins -- Probing Structural and Electronic Parameters in Randomly Oriented Metalloproteins by Orientation-Selective ENDOR Spectroscopy -- Molecular Sophe: An Integrated Approach to the Structural Characterization of Metalloproteins: The Next Generation of Computer Simulation Software -- Spin-Hamiltonian Parameters from First Principle Calculations: Theory and Application -- IRON PROTEINS -- EPR of Mononuclear Non-Heme Iron Proteins -- Binuclear Non-Heme Iron Enzymes -- Probing the Structure#x2013;Function Relationship of Heme Proteins Using Multifrequency Pulse EPR Techniques -- EPR Studies of the Chemical Dynamics of NO and Hemoglobin Interactions -- NICKEL AND COPPER ENZYMES -- EPR Investigation of [NiFe] Hydrogenases -- Unique Spectroscopic Features and Electronic Structures of Copper Proteins: Relation to Reactivity -- METALS IN MEDICINE -- Insulin-Enhancing Vanadium Pharmaceuticals: The Role of Electron Paramagnetic Resonance Methods in the Evaluation of Antidiabetic Potential -- Chromium in Cancer and Dietary Supplements -- High-Frequency EPR and ENDOR Characterization of MRI Contrast Agents.
520 _aHigh Resolution EPR: Applications to Metalloenzymes and Metals in Medicine Prof. Graeme Hanson, University of Queensland and Prof. Lawrence Berliner, University of Denver Metalloproteins are involved in a variety of biologically important processes, including metal ion and oxygen transport, biosynthesis, electron transfer, biodegradation, drug metabolism, proteolysis and peptide hydrolysis, environmental oxygen, sulphur, and nitrogen cycles, and disease states. High-resolution EPR spectroscopy is crucial in determining the geometric and electronic structural characterization of the redox cofactors in metalloenzymes, which is essential for understanding their reactivity in complex biological systems. This volume, Part I of a two-volume set, covers high-resolution EPR methods, computer simulation, density functional theory, and their application to iron proteins, nickel, and copper enzymes and metals in medicine. The following chapters, written by experts in their fields, include: Advanced Pulse EPR Methods for the Characterization of Metalloproteins: Jeffrey Harmer, George Mitrikas, and Arthur Schweiger Probing Structural and Electronic Parameters in Randomly Oriented Metalloproteins by Orientation-Selective ENDOR Spectroscopy: Reinhard Kappl, Gerhard Bracic, and Jürgen Hüttermann Molecular Sophe: An Integrated Approach to the Structural Characterization of Metalloproteins: The Next Generation of Computer Simulation Software: Graeme Hanson, Christopher Noble, and Simon Benson Spin-Hamiltonian Parameters from First Principle Calculations: Theory and Application: Frank Neese EPR of Mononuclear Non-Heme Iron Proteins: Betty Gaffney Binuclear Non-Heme Iron Enzymes: Nataša Mitic, Gerhard Schenk, and Graeme Hanson Probing the Structure–Function Relationship of Heme Proteins Using Multifrequency Pulse EPR Techniques: Sabine Van Doorslaer EPR Studies of the Chemical Dynamics of NO and Hemoglobin Interactions: Benjamin Luchsinger, Eric Walter, Lisa Lee, Jonathan Stamler, and David Singel EPR Investigation of [NiFe] Hydrogenases: Maurice van Gastel and Wolfgang Lubitz Unique Spectroscopic Features and Electronic Structures of Copper Proteins: Relation to Reactivity: Jungjoo Yoon and Edward Solomon Insulin-Enhancing Vanadium Pharmaceuticals: The Role of Electron Paramagnetic Resonance Methods in the Evaluation of Antidiabetic Potential: Barry Liboiron Chromium in Cancer and Dietary Supplements: Aviva Levina, Rachel Codd, and Peter Lay High-Frequency EPR and ENDOR Characterization of MRI Contrast Agents: Arnold Raitsimring, Andrei Astashkin, and Peter Caravan.
650 0 _aMedicine.
650 0 _aBiomedical engineering.
650 0 _aMaterials science.
650 1 4 _aBiomedicine.
650 2 4 _aBiomedicine general.
650 2 4 _aMaterials Science, general.
650 2 4 _aBiomedical Engineering.
655 7 _aElectronic books.
_2local
700 1 _aBerliner, Lawrence.
_eeditor.
700 1 _aHanson, Graeme.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387848556
830 0 _aBiological Magnetic Resonance,
_x0192-6020 ;
_v28
856 4 0 _uhttp://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-0-387-84856-3
912 _aZDB-2-SBL
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