000			03546nam a22005655i 4500
001			978-3-540-76735-0
003			DE-He213
005			20160615111953.0
007			cr nn 008mamaa
008			100301s2009 gw | s |||| 0|eng d
020			_a9783540767350 _9978-3-540-76735-0
024	7		_a10.1007/978-3-540-76735-0 _2doi
049			_aAlfaisal Main Library
050		4	_aR895-920
072		7	_aMMN _2bicssc
072		7	_aMED080000 _2bisacsh
082	0	4	_a616.07548 _223
100	1		_aVallabhajosula, Shankar. _eauthor.
245	1	0	_aMolecular Imaging _h[electronic resource] : _bRadiopharmaceuticals for PET and SPECT / _cby Shankar Vallabhajosula.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2009.
300			_aXX, 372 p. 221 illus., 139 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aMolecular Imaging: Introduction -- Science of Atomism: A Brief History -- Atoms and Radiation -- Radioactivity -- Production of Radionuclides -- PET and SPECT Scanners -- Chemistry: Basic Principles -- Cell and Molecular Biology -- Radiopharmaceuticals -- Chemistry of Radiohalogens (F, Br. and I) -- Chemistry of Organic Radionuclides (C, N, and O) -- Chemistry of Metal Radionuclides (Rb, Ga, In, Y, Cu and Tc) -- Qouality Control of PET Rediopharmaceuticals -- Pharmacokinetics and Modeling -- Molecular Imaging in Oncology -- Molecular Imaging in Neurology and Psychiatry -- Molecular Imaging in Cardiology -- Molecular Imaging of Gene Expression and Cell Trafficking -- Radiation Dosimetry and Protection -- Radiopharmaceuticals: Drug Development and Regulatory Issues.
520			_aRadioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.
650		0	_aMedicine.
650		0	_aRadiology.
650		0	_aNuclear medicine.
650		0	_aCardiology.
650		0	_aOncology.
650		0	_aNeurology.
650		0	_aPathology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aNuclear Medicine.
650	2	4	_aImaging / Radiology.
650	2	4	_aPathology.
650	2	4	_aOncology.
650	2	4	_aCardiology.
650	2	4	_aNeurology.
655		7	_aElectronic books. _2local
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783540767343
856	4	0	_uhttp://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-3-540-76735-0
912			_aZDB-2-SME
942			_2lcc _cEBOOKS
999			_c297176 _d297176