000 03665cam a2200421 i 4500
001 1398568560
003 US-DLC
005 20251110094526.0
008 230923t20242024nyum b a 1 0 eng d
020 _a9781324050681
_q(hardcover)
020 _z1324050683
_q(hardcover)
035 _a(OCoLC)1398568560
_z(OCoLC)1435584164
040 _aau
_beng
_erda
_cau
049 _aAlfaisal Main Library
050 4 _aQP623
_b.C43 2024
100 1 _aCech, Thomas,
_eauthor.
245 1 4 _aThe catalyst :
_bRNA and the quest to unlock life's deepest secrets /
_cThomas R. Cech.
246 3 0 _aRNA and the quest to unlock life's deepest secrets.
250 _aFirst edition.
260 _c2024
264 1 _aNew York, NY :
_bW. W. Norton & Company,
_c2024
264 4 _c�2024.
300 _a292 pages :
_billustrations ;
_c24 cm.
336 _atext
_btxt
_2rdacontent.
337 _aunmediated
_bn
_2rdamedia.
338 _avolume
_bnc
_2rdacarrier.
504 _aIncludes bibliographical references (pages 251-280) and index.
505 0 _aIntroduction: The age of RNA -- Part I: The search. The messenger -- Splice of life -- Going it alone -- The shape of a shapeshifter -- The mothership -- Origins -- Part II: The cure. Is the fountain of youth a death trap? -- As the worm turns -- Precise parasites, sloppy copies -- RNA versus RNA -- Running with scissors -- Epilogue: The future of RNA.
520 _a"One of Literary Hub's Most Anticipated Books of 2024. Exploring the most transformative breakthroughs in biology since the discovery of the double helix, a Nobel Prize-winning scientist unveils the RNA age. For over half a century, DNA has dominated science and the popular imagination as the 'secret of life.' But over the last several decades, a quiet revolution has taken place. In a series of breathtaking discoveries, the biochemist Thomas R. Cech and a diverse cast of brilliant scientists have revealed that RNA -- long overlooked as the passive servant of DNA -- sits at the center of biology's greatest mysteries: How did life begin? What makes us human? Why do we get sick and grow old? In The Catalyst, Cech finally brings together years of research to demonstrate that RNA is the true key to understanding life on Earth, from its very origins to our future in the twenty-first century. A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health. We learn how RNA -- once thought merely to transmit DNA's genetic instructions to the cell's protein-making machinery -- may have jump-started life itself, and how, at the same time, it can cut our individual lives short through viral diseases and cancer. We see how RNA is implicated in the aging process and explore the darker depths of the supposed fountain of youth, telomerase. And we catch a thrilling glimpse into how RNA-powered therapies -- from CRISPR, the revolutionary tool that uses RNA to rewrite the code of life, to the groundbreaking mRNA vaccines that have saved millions during the pandemic, and more -- may enable us to improve and even extend life beyond nature's current limits. Written by one of our foremost scientists, The Catalyst is a must-read guide to the present and future of biology and medicine." --
590 _aGOBI Library Solutions from EBSCO
_bNJB.
650 0 _aRNA.
650 0 _aGenomics.
650 2 _aRNA.
650 2 _aGenomics.
655 0 _aPrint books.
_2local
_94
942 _2lcc
_cBOOKS
951 _aSubaccount: 3430-10
999 _c607881
_d607881